COLOXAN WS
Doxycycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria like Bordetella, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Doxycycline is also active against Chlamydia, Mycoplasma and Rickettsia spp. The action of doxycycline is based on inhibition of bacterial protein synthesis. Doxycycline has good affinity towards the lungs and is therefore especially useful for treatment of bacterial Respiratory infections. Colistin is an antibiotic from the group of polymyxins with bactericidal action against mainly Gram-negative bacteria like E. coli, Haemophilus and Salmonella spp. Polymyxins interact strongly with phospholipids and penetrate into and disrupt the structure of cell membranes. Administered orally, colistin is poorly resorbed and, therefore, performs its action predominantly gastrointestinally.
| Active Ingredients | |
|---|---|
| Doxycycline hyclate | 100 mg/g |
| Colistin sulphate | 1 200 000 IU/g |
| Parasites, Vectors & Organisms Controlled | |
| Bordetella | ✓ |
| Campylobacter | ✓ |
| Chlamydia | ✓ |
| E. coli | ✓ |
| Haemophilus | ✓ |
| Mycoplasma | ✓ |
| Pasteurella | ✓ |
| Rickettsia | ✓ |
| Salmonella | ✓ |
| Staphyloccocus | ✓ |
| Streptococcus | ✓ |
Gastrointestinal and Respiratory infections caused by micro-organisms sensitive to doxycycline and/or colistin like Bordetella, Campylobacter, Chlamydia, E. coli, Klebsiella, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus and Streptococcus spp. in calves, goats, poultry, sheep and swine.
Hypersensitivity to tetracyclines and/or polymyxins.
Administration to animals with seriously impaired renal and/or hepatic functions, animals with an active microbial digestion or animals producing milk or eggs for human consumption.
Concurrent administration of penicillins, cephalosporins, quinolones and cycloserine.
Application Rate
For oral administration.
Dose rates/directions for use:
Calves:
Twice daily 1 g per 20 kg body weight for 4 – 5 days.
Note: for pre-ruminant calves, lambs and kids only.
For oral administration.
Dose rates/directions for use:
Sheep & Goats:
Twice daily 1 g per 20 kg body weight for 4 – 5 days.
Note: for pre-ruminant calves, lambs and kids only.
For oral administration.
Dose rates/directions for use:
1 kg per 1000 litres of drinking water for 4 – 5 days.
For oral administration.
Dose rates/directions for use:
1 kg per 2000 litres of drinking water for 4 – 5 days.