For vaccination of healthy cattle, including pregnant cows, as an aid in preventing infectious bovine rhinotracheitis caused by infectious bovine rhinotracheitis (IBR) virus, bovine viral diarrhea caused by bovine viral diarrhea (BVD) virus Type 1, and disease caused by parainfluenza3 (PI3) virus and bovine respiratory syncytial virus (BRSV). CattleMaster 4 is a freeze-dried preparation of chemically altered strains of IBR and PI3 viruses and modified live BRSV plus a liquid, adjuvanted preparation of inactivated cytopathic and noncytopathic BVD Type 1 virus strains. The liquid component is used to rehydrate the freeze-dried component. Viral antigens are propagated on an established cell line. This product is adjuvanted with aluminum hydroxide to enhance immune response.